. Case Study Assignment
Read the below case study. You may use your textbook for research. Type your answers in a document and upload to this assignment.
Patient X is a 75 year old female who had a cystocele repair 10 days ago. Upon admission to the hospital, her urine culture showed >100,000 CFU/mL of an E. coli strain susceptible to all tested antibiotics. She was given oral cephalexin for 7 days post-operation and was discharged after day 3. Patient X begins to exhibit diarrhea for 3 days, after 10 days post-op. Patient complained of loose watery stools, showing no blood, abdominal cramps and emesis. Patient’s stats are pulse rate of 95/min, respiration rate of 25/min, temp is 39 degrees Celsius, and blood pressure is 117/54 mm Hg. WBC count is normal, but shows many (54%) polymorphonuclear cells (immature). Patient X’s electrolytes, lipase, liver enzymes and examination were all normal.
Cultures returned negative for Salmonella, Shigella, Yersinia, and Campylobacter spp.
1, What microbe is causing Patient X’s diarrhea?
2. What predisposing factors did Patient X have for this infection? How did those factors aid in her susceptibility?
3. As a nosocomial pathogen, why is this microbe problematic? Explain.
4. What virulence factors does this organism produce, and what roles do these factors play in the pathogenesis of disease?
5, Discuss three different types of therapeutic strategies that can be used to treat this disease.
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